B.S., Stony Brook University, Stony Brook, NYM.S., Ph.D., Albert Einstein College of Medicine, Bronx, NY
Dr. Bouklas is an Assistant Professor in the Department of Biomedical Sciences, in the School of Health Professions and Nursing.
Dr. Bouklas earned a B.S. in Biology from Stony Brook University and the Women in Science Engineering Program, and earned an M.S. and a Ph.D. in Biomedical Sciences (Microbiology and Immunology) from Albert Einstein College of Medicine. She did a postdoctoral fellowship in the Department of Medicine (Division of Infectious Diseases) at Stony Brook University before joining LIU-Post in 2016.
Dr. Bouklas investigates the persistence and resistance of fungal pathogens in immunocompromised hosts. During her doctorate, she established aging as a novel virulence factor in Cryptococcus neoformans, a pathogen that afflicts HIV+/AIDS patients. This has led to her work in Candida glabrata, which is notorious for causing infections in diabetic and elderly patients. Dr. Bouklas’ work has significantly contributed to the fields of microbiology and infectious diseases, and has been disseminated in several manuscripts and reviews, as well as presentations at national and international conferences.
Microbiology, Infectious diseases, Immunology, Antifungals
- Bouklas, T.*, Diago-Navarro, E.*, Wang, X., Fenster, M., Fries, B.C. 2016. Characterization of the virulence of Cryptococcus neoformans in an insect model. Virulence. 6(8):809-813. (*equal contribution)
- Jain, N., Bouklas, T., Gupta, A., Varshney, A.K., Orner, E., Fries, B.C. 2016. ALL2, a homologue of ALL1, contributes a distinct role in regulating pH homeostasis in the pathogen, Cryptococcus neoformans. Infection and Immunity. 84(2):439-451.
- Bouklas, T., Fries, B.C. 2015. Aging: An emergent phenotypic trait that contributes to the virulence of Cryptococcus neoformans. Future Microbiology. 10(2):191-7.
- Bouklas, T., Fries, B.C. 2014. Aging as an emergent factor that contributes to phenotypic variation in C. neoformans. Fungal Genetics and Biology. 78:59-64.
- Bouklas, T., Pechuan, X., Goldman, D.L., Edelman, B., Bergman, A., Fries, B.C. 2013. Old Cryptococcus neoformans cells contribute to virulence in chronic cryptococcosis. mBio. 4(4):e00455-13.
- Bouklas, T., Fries, B.C. 2013. Cryptococcus neoformans constitutes an ideal model organism to unravel the contribution of cellular aging to the virulence of chronic infections. Current Opinion in Microbiology. 16(4):391-397.
Lectures and Presentations
- Modulation of replicative life span in Cryptococcus neoformans: implications for virulence. International Conference on Cryptococcus and Cryptococcosis, Foz do Iguacu, Brazil. March 2016.
- Implications of a heterogeneous age distribution for a Candida glabrata population. Workshop on Cellular Heterogeneity and Evolution, Laufer Center for Physical and Quantitative Biology, Stony Brook University, Stony Brook, NY. 2016.
- The resilience of old age: Replicative aging contributes to the virulence of Candida glabrata. Women in Medicine Day, Stony Brook University, Stony Brook, NY. May 2015.
- Replicative Aging in the human pathogen Candida glabrata. American Society of Microbiology General Meeting, Boston, MA. May 2014.
- Consequences of SIR2 regulation on the pathogenesis of Cryptococcus neoformans. International Conference on Cryptococcus and Cryptococcosis, Amsterdam, Netherlands. May 2014.
- Investigations on replicative life span of Cryptococcus neoformans strains and the relevance of these findings for virulence. Congress of the International Society for Human and Animal Mycology, Berlin, Germany. June 2012.
- In vitro and in vivo investigation of RLS of all1 null mutant in Cryptococcus neoformans. International Conference on Cryptococcus and Cryptococcosis, Charleston, SC. May 2011.
- NIH Training Grant, “HIV, AIDS and Opportunistic Infections.”
- Sigma Xi Excellence in Research Award
- Student Design and Research Award, Biomedical Engineering Society
- American Society of Microbiology
- Metropolitan Association of College and University Biologists