Faculty & Research Interests

Faculty

Jaclyn Novatt, Ph.D.
Assistant Professor of Pharmacy Practice
Jaclyn.Novatt@liu.edu
(718) 780-4187


Education
Ph.D., Biomedical Sciences, The Rockefeller University, New York, NY
M.S., Chemistry, Brandeis University, Waltham, MA
B.A., Chemistry, Brandeis University, Waltham, MA

Short Biography


Dr. Novatt is a biochemist who is passionate about science and science education.
She was a Howard Hughes Medical Institute pre-doctoral fellow at the Rockefeller University, where she worked with Dr. Michael Rout to study how proteins move in and out of the nucleus of cells. After receiving her Ph.D. in 2009, she moved to Cold Spring Harbor Laboratory where sthe studied the basic mechamisms of RNA splicing and its connection to human disease with Dr. Adrian Krainer. There, she received a postdoctoral training fellowship from the National Cancer Institute.
Since 2008, Dr. Novatt has taught chemistry, biochemistry, genetics, and human biology as an adjunct professor at several colleges and universities throughout the NY metro area.
She came to LIU in January 2017 with the goal of increasing our pharmacy students’ exposure to research. To this end, she has developed a research APPE and two research-based electives – “Introduction to Research” and “From Petri Dish to Pharmacy.” 
In addition to science, Dr. Novatt has a background in theater and improv. She loves working with students to improve their communication skills using improv-based activities.
Research Synopsis

Scholarship of Teaching and Learning: Developing, implementing, and evaluating novel approaches to teach biomedical science, research methods, and communication skills.


Selected Publications
  • Hough LE, Dutta K, Sparks S, Temel DB, Kamal A, Tetenbaum-Novatt J, Rout MP, Cowburn D. The Molecular Mechanism of Nuclear Transport Revealed by Atomic Scale Measurements. eLife 2015 Sept 15; 4
  • Tetenbaum-Novatt J, Hough LE, Mironska R, McKenney AS, Rout MP. Nucleocytoplasmic transport: a role for nonspecific competition in karyopherin-nucleoporin interactions. Mol Cell Proteomics 2012 May; 11(5): 31-46
  • Tetenbaum-Novatt J and Rout MP. The mechanism of nucleocytoplasmic transport through the NPC. Cold Spring Harbor Symp Quant Biol. 2010; 75:567-84.
  • Jovanovic-Talisman T, Tetenbaum-Novatt J, McKenney AS, Zilman A, Peters R, Rout MP, Chait BT. Artificial nanopores that mimic the transport selectivity of the nuclear pore complex. Nature. 2009 Feb 19; 457(7232): 1023-7
  • Timney BL, Tetenbaum-Novatt J, Agate DS, Williams R, Zhang W, Chait BT, Rout MP. Simple kinetic relationships and non-specific competition govern nuclear import rates in vivo. J Cell Biol. 2006 Nov 20; 175(4): 579-93
  • D’Aquino A, Tetenbaum-Novatt J, Ringe D. Mechanism of metal ion activation of the Diphtheria Toxin Repressor DtxR. PNAS USA 2005 Dec 20; 102(51): 18408-13
  • Strambio-de-Castilla C, Tetenbaum-Novatt J, Imai BS, Chait BT, Rout MP. A Method for the rapid and efficient elution of native affinity-purified Protein A tagged complexes. J Proteome Res. 2005 Nov-Dec; 4(6): 2250-6
  • Miller LM, Novatt JT, Hammerman D, Carlson CS. Alterations in mineral composition observed in osteoarthritic joints of cynomolgus monkeys. Bone, 2004 Aug; 35(2): 49-506
  • Tetenbaum J, Miller LM. A new spectroscopic approach to examining the role of disulfide bonds in the structure and unfolding of soybean trypsin inhibitor. Biochemistry, 2001 Oct 9; 40(40): 12215-9

CONTACT

LIU Pharmacy
John M. Pezzuto, A.B., Ph.D.
Dean