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Faculty


Robert Young

Research Assistant Professor, Arthur G. Zupko’s Systems Pharmacology and Pharmacogenomics

Ph.D., Colorado State UniversityJ.D., Columbia University School of LawB.B.A., University of Texas, Austin (Finance)

Description

Dr. Robert B. Young has joined the Arnold and Marie Schwartz College of Pharmacy and Health Sciences, LIU Brooklyn as a research assistant professor in metabolomics. He will work in the Division of Systems Pharmacology and Pharmacogenomics at The Samuel J. and Joan B. Williamson Institute. 

Dr. Young holds degrees from the University of Texas, Austin and from Columbia University. He graduated from Colorado State University in 2014 with a Ph.D. in environmental chemistry, and has considerable experience using targeted and nontargeted mass spectrometry analyses to detect and identify environmental pollutants and their transformation products in complex samples ranging from Arctic seal blubber to hydrocarbon contaminated soils and groundwater. Dr. Young’s analytical chemistry experience includes liquid and gas chromatography, tandem mass spectrometry, and high resolution mass spectrometry (time-of-flight, Orbitrap, and ion cyclotron resonance). He also has substantial programming experience, and has developed custom scripts to screen nontargeted mass spectrometry data for known environmental contaminants and identify compositional differences in complex environmental samples with more than 20,000 unique detected features.



Specialties

Research Interests:

In the systems pharmacology and pharmacogenomics lab, Dr. Young will be responsible for the day-to-day operation of the lab’s Waters Xevo G2-XS liquid chromatography quadrupole time-of flight mass spectrometer, Waters Xevo TQ-S micro liquid chromatography triple quadrupole mass spectrometer, and Agilent 5977B gas chromatography mass spectrometry systems. Dr. Young will perform targeted and nontargeted metabolomics and lipidomics analyses on biological fluids and tissue samples to support method development in precision medicine and investigate the mechanisms and treatment of progressive liver and other diseases. His current projects include collaborations with researchers in the Netherlands, Czech Republic and Harvard University to examine the mechanisms of encephalopathy in certain individuals treated with an anti-cancer drug, the occurrence and progression of multiple sclerosis in mouse models and the mechanisms of hepatic fibrogenesis in small animal models.

Publications

Scientific Journals

2018
• Young, R. B.; Avneri-Katz, S.; McKenna, A. M.; Chen, H.; Bahureksa, W.; Polubesova, T.; Chefetz, B.; Borch, T. Composition-Dependent Sorptive Fractionation of Anthropogenic Dissolved Organic Matter by Fe(III)-Montmorillonite. Soil Systems, 2018, 2, 14, doi: 10.3390/soilsystems2010014 (Invited article for special issue on soil organic matter dynamics). 

2017
• Hagemann, N.; Joseph, S.; Schmidt, H. P.; Kammann, C. I.; Harter, J.; Borch, T.; Young, R. B.; Varga, K.; Taherymoosavi, S.; Elliott, K. W.; McKenna, A.; Albu, M.; Mayrhofer, C.; Obst, M.; Conte, P.; Dieguez-Alonso, A.; Behrens, S.; Kappler, A. Organic coating on biochar explains its nutrient retention and stimulation of soil fertility. Nature Communications, 2017, 8(1), 1089. doi: 10.1038/s41467-017-01123-0. 2017

• Avneri-Katz, S.; Young, R. B.; McKenna, A. M.; Chen, H.; Corilo, Y. E.; Polubesova, T.; Borch, T.; Chefetz, B. Adsorptive fractionation of dissolved organic matter (DOM) by mineral soil: Macroscale approach and molecular insight. Organic Geochemistry, 2017, 103:113-124. doi: 10.1016/j.orggeochem.2016.11.004.

2014
• Young, R. B.; Chefetz, B.; Liu, A.; Desyaterik, Y.; Borch, T. Direct photodegradation of lamotrigine (an antiepileptic) in simulated sunlight – pH influenced rates and products. Environmental Science: Processes & Impacts 2014, 16, (4), 848-857, doi: 10.1039/c3em00581j (Invited article for special issue on aquatic photochemistry).

2013
• Young, R. B.; Latch, D. E.; Mawhinney, D. B.; Nguyen, T. H.; Davis, J. C. C.; Borch, T. Direct photodegradation of androstenedione and testosterone in natural sunlight: Inhibition by dissolved organic matter and reduction of endocrine disrupting potential. Environmental Science & Technology, 2013, 47 (15), 8416-8424, doi: 10.1021/es401689j.

2011
• Mawhinney, D. B.; Young, R. B.; Vanderford, B. J.; Borch, T.; Snyder, S. A. Artificial sweetener sucralose in U.S. drinking water systems. Environmental Science & Technology, 2011, 45 (20), 8716-8722, doi: 10.1021/es202404c.

• Pisarenko, A. N.; Young, R.; Quinones, O.; Vanderford, B. J.; Mawhinney, D. B. Two new methods of synthesis for the perbromate ion: Chemistry and determination by LC-MS/MS. Inorganic Chemistry, 2011, 50 (18), 8691-8693, doi: 10.1021/ic201329q.

• Yang, Y. Y.; Pereyra, L. P.; Young, R. B.; Reardon, K. F.; Borch, T. Testosterone-mineralizing culture enriched from swine manure: Characterization of degradation pathways and microbial community composition. Environmental Science & Technology, 2011, 45 (16), 6879-6886, doi: 10.1021/es2013648.

2010
• Yang, Y. Y.; Borch, T.; Young, R. B.; Goodridge, L. D.; Davis, J. G. Degradation kinetics of testosterone by manure-borne bacteria: Influence of temperature, pH, glucose amendments, and dissolved oxygen. Journal of Environmental Quality, 2010, 39 (4), 1153-1160, doi: 10.2134/jeq2009.0112.

Book Chapter

2009

• Young, R. B.; Borch, T. Sources, presence, analysis, and fate of steroid sex hormones in freshwater ecosystems - A review. In Aquatic Ecosystem Research Trends, Nairne, G. H., Ed. Nova Science Publishers, Inc.: Hauppauge, NY, USA, 2009; pp 103-164, ISBN: 978-1-60692-772-4.

Lectures and Presentations


Honors/Awards


Professional Affiliations