Maged-Hemida

Description

Dr. Hemida earned his Ph.D. in 2009 from the Pathobiology Department at the Ontario Veterinary College (OVC), University of Guelph, Canada, where he conducted molecular and biological characterization studies on turkey coronavirus. Following his Ph.D., he pursued postdoctoral training at the Centre for Heart Lung Innovation, Department of Pathology and Laboratory Medicine, College of Medicine, University of British Columbia (UBC), Canada. During his postdoctoral work, Dr. Hemida explored the roles of small RNA molecules, particularly microRNAs, and host transcription factors in the molecular pathogenesis of Coxsackievirus B3 (CVB3). His research identified key microRNAs involved in regulating CVB3 infection and pathogenesis both in vitro and in murine models.

Dr. Hemida obtained his BVSc (DVM equivalent) and MVSc degrees from the University of Kafrelsheikh, Egypt. Before joining LIU College of Veterinary Medicine as a full professor, he held multiple academic positions across North America and the Middle East, progressing from an instructor/demonstrator position in virology to senior academic ranks.

Dr. Hemida is a founding faculty of the Lewyt College of Veterinary Medicine as well as the LIU Center for Excellence in Research.

Research

Dr. Hemida’s research focuses on understanding virus-host interactions and developing innovative solutions for preventing and controlling viral diseases across species. His primary areas of interest include:

1- AI-Driven Vaccines/Drugs Development: Integrating artificial intelligence tools to design and develop novel vaccines against major viral diseases affecting humans, livestock, and poultry.

2- Coronaviruses/ Host Interaction: Investigating the roles of small RNA molecules (such as microRNAs), cellular receptors, and host enzymes that fine-tune BCoV replication and tissue tropism.

3- Molecular Characterization of the common Feline Viruses in Long Island: Conducting molecular and serological surveillance of common feline viruses in feral cat populations, including Feline Infectious Peritonitis Virus (FIPV), Feline Immunodeficiency Virus (FIV), and Feline Leukemia Virus (FeLV).

Distinctions & Awards

Long Island University, USA

• Zoetis Research Award: 2025
• Newton Award for Excellence in Teaching

University of British Columbia, Canada

• Canadian Institutes of Health Research (CIHR) Fellowship: 2009-2012
• IMPACT-Fellowship: 2009-2012
• Heart and Stroke Foundation of Canada (HSFC) Award: 2010-2012

University of Guelph, Canada

• University of Guelph Scholarship: 2005
• University of Guelph Scholarship: 2006
• Dr. Wilson Henderson Memorial Scholarship (OVC): 2006
• Dr. Wilson Henderson Memorial Scholarship (OVC): 2007
• Soren Rosendal Memorial Research Prize: 2009

King Faisal University, Saudi Arabia

• Almarai Distinguished Research prize in the Gulf countries
• KFU top research award

Kafrelsheikh University, Egypt

• Valedictorian-Faculty of Veterinary Medicine, Kafrelsheikh University: Class-1996
• Top student award- Faculty of Veterinary Medicine, Kafrelsheikh University: 1991-1996

Selected Publications

• Nithyadevi Duraisamy, Abid Ullah Shah, Mohd Yasir Khan, Mohammed Cherkaoui, Hemida MG.. 2025. Artificial Intelligence-Guided Design of some Pan-H5N1-clade 2.3.4.4b Mosaic DNA-based vaccines to combat the circulating HPAI in birds. Vaccines. 10.21203/rs.3.rs-6711963/v1.
• Mohd Yasir Khan, Abid Ullah Shah, Nithyadevi Duraisamy, Mohammed Cherkaoui and Hemida MG.. 2025. In silico design/repurposing of some Nucleoside analogs as Antiviral inhibitors targeting some Key Proteins of the Avian H5N1 Clade 2.3.4.4b Using Molecular Docking and Simulation. (Viruses).
• Shah AU, Hemida MG. The dual actions of miRNA16a in restricting Bovine Coronavirus replication through downregulation of Furin and enhancing the host immune response. Sci Rep. 2024;14(1):29308.
• Shah AU, Gauger P, Hemida MG. Isolation and molecular characterization of an enteric isolate of the genotype-Ia bovine coronavirus with notable mutations in the receptor binding domain of the spike glycoprotein. Virology. 2025;603:110313.
• Khan MY, Shah AU, Duraisamy N, ElAlaoui RN, Cherkaoui M, Hemida MG. Leveraging Artificial Intelligence and Gene Expression Analysis to Identify Some Potential Bovine Coronavirus (BCoV) Receptors and Host Cell Enzymes Potentially Involved in the Viral Replication and Tissue Tropism. Int J Mol Sci. 2025;26(3).
• Shah AU, Hemida MG. The ex vivo infection model of the peripheral bovine mononuclear cells (PBMCs) and the bovine spleen cells with the bovine coronavirus (BCoV) induced a differential expression of the host cytokine genes profiles and modulates the virus replication. Virology. 2024;600:110259.
• Shah AU, Hemida MG. The Potential Roles of Host Cell miRNAs in Fine-Tuning Bovine Coronavirus (BCoV) Molecular Pathogenesis, Tissue Tropism, and Immune Regulation. Microorganisms. 2024;12(5).
• Duraisamy N, Khan MY, Shah AU, Elalaoui RN, Cherkaoui M, Hemida MG. Machine learning tools used for mapping some immunogenic epitopes within the major structural proteins of the bovine coronavirus (BCoV) and for the in silico design of the multiepitope-based vaccines. Front Vet Sci. 2024;11:1468890.
• Al-Mubarak AIA, Al-Kubati AAG, Sheikh A, Abdelaziz AM, Hussen J, Kandeel M, Hemida MG. Detection of Avian Orthoavulavirus-1 genotypes VI.2.1 and VII.1.1 with neuro-viscerotropic tropism in some backyard pigeons (Columbidae) in Eastern Saudi Arabia. Front Vet Sci. 2024;11:1352636.
• Hemida MG, Egamberdieva D, Malik YS. Editorial: Coronaviruses from the One Health perspective. Front Microbiol. 2023;14:1338529.
• van Doremalen N, Letko M, Fischer RJ, Bushmaker T, Schulz J, Yinda CK, Hemida MG, et al. Surface‒Aerosol Stability and Pathogenicity of Diverse Middle East Respiratory Syndrome Coronavirus Strains, 2012‒20.
• Hemida MG, Alnaeem A. Some One Health based control strategies for the Middle East respiratory syndrome coronavirus. One Health. 2019 Aug 21;8:100102. doi: 10.1016/j.onehlt.2019.100102. PMID: 31485476; PMCID: PMC6715958.
• Hemida MG, Ye X, Zhang HM, Hanson PJ, Liu Z, McManus BM, Yang D. MicroRNA-203 enhances coxsackievirus B3 replication through targeting zinc finger protein-148. Cell Mol Life Sci. 2013 Jan;70(2):277-91. doi: 10.1007/s00018-012-1104-4. Epub 2012 Jul 29. PMID: 22842794; PMCID: PMC11113921.
• Hanson PJ, Ye X, Qiu Y, Zhang HM, Hemida MG, Wang F, Lim T, Gu A, Cho B, Kim H, Fung G, Granville DJ, Yang D. Cleavage of DAP5 by coxsackievirus B3 2A protease facilitates viral replication and enhances apoptosis by altering translation of IRES-containing genes. Cell Death Differ. 2016 May;23(5):828-40. doi: 10.1038/cdd.2015.145. Epub 2015 Nov 20. PMID: 26586572; PMCID: PMC4832101.

Scientific Contributions and Supervision

Dr. Hemida has published over 100 scientific peer-reviewed papers in top-tier peer-reviewed journals, including Lancet Respiratory Medicine, PNAS, Emerging Infectious Diseases (EID), and Emerging Microbes & Infections (EMI). He has supervised numerous trainees, including master’s and Ph.D. students, postdoctoral fellows, and research assistants. He has also secured competitive grants from renowned funding agencies worldwide.